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HEALTH-VIRUS-BRITAIN-VACCINE, FACTS
Five things to know about landmark UK vaccine
LONDON, Dec 30, 2020 (BSS/AFP) – Cheap and easy to store, the
AstraZeneca/Oxford vaccine approved by the British regulator on Wednesday has
given a shot in the arm to the global fight against coronavirus.
Here are five facts about the much-anticipated vaccine.
– Practicality –
The AstraZeneca/Oxford vaccine has the major advantages of being
inexpensive, costing about o2.50 ($3.40, 2.75 euros) per dose, and easy to
store.
It can be kept at normal refrigerator temperatures of between two and
eight degrees Celsius, making it ideal for large-scale vaccination programs.
By contrast, the Moderna vaccine needs to be stored at -20C, while the
Pfizer/BioNTech product must be kept at -70C.
– Mutant strain –
The vaccine should be capable of fighting the new variant of the
coronavirus responsible for a surge of cases in the United Kingdom, according
to AstraZeneca chief executive Pascal Soriot.
“So far, we think the vaccine should remain effective. But we can’t be
sure, so we’re going to test that,” he told the Sunday Times.
New versions are being developed just in case, he revealed, adding: “You
have to get prepared.”
– British product –
The vaccine developed by British firm AstraZeneca, working alongside
Oxford University, is the second to be approved by the independent Medicines
and Healthcare products Regulatory Agency (MHRA).
The Pfizer/BioNTech vaccine has been deployed in Britain since December 8,
with almost 800,000 receiving their first dose, according to British Prime
Minister Boris Johnson.
His government is battling one of the world’s worst outbreaks, with more
than 71,000 deaths so far of those testing positive for the disease.
Britain has ordered 100 million doses of the AstraZeneca/Oxford vaccine,
40 million of which will be available by the end of March, with vaccinations
scheduled to begin on January 4.
AstraZeneca said it expects to be able to manufacture about three billion
doses of its vaccine worldwide in 2021.
– Chimpanzees –
The vaccine is “virus-vectored”, meaning it is a version of a virus that
normally infects chimpanzees and has been modified with a portion of the
Covid-19 coronavirus called the “spike protein” to fire the immune system.
Once in human cells, the vaccine should help stimulate the production of
antibodies that recognizee the virus.
The vaccine is “safe and effective”, according to data published by The
Lancet medical journal on December 8, with only one of the of the 23,754
volunteers who participated in the trials experiencing “possibly-related
severe side effects”.
This was a case of rare neurological condition transverse myelitis that
forced the temporary suspension of trials.
– Result Confusion-
The British laboratory announced in interim findings in November that its
vaccine was on average 70 percent effective, compared with more than 90
percent for Pfizer/BioNTech and Moderna.
The efficacy of the AstraZeneca/Oxford vaccine was 90 percent for
volunteers who first received only a half-dose and then a full dose one month
later, but only 62 percent for another group that was vaccinated with two
full doses one month apart.
The injection of a half-dose was conducted by accident, raising criticism
over the robustness of the results and prompting the company to announce on
November 26 that an “additional study” would be held into the efficacy of the
reduced dosage.
“We think we have figured out the winning formula and how to get efficacy
that, after two doses, is up there with everybody else,” Soriot told the
Sunday Times.
BSS/AFP/IJ/1637 hrs