ZCZC
BFF-27
SCIENCE-CHINA-GENETICS
Second woman carrying gene-edited baby in China: state media
BEIJING, Jan 21, 2019 (BSS/AFP) – A researcher who claimed to have created
the world’s first genetically-edited babies will face a Chinese police
investigation, state media said Monday, as authorities confirmed that a
second woman fell pregnant during the experiment.
He Jiankui shocked the scientific community last year after announcing he
had successfully altered the genes of twin girls born in November to prevent
them from contracting HIV.
He had told a human genome forum in Hong Kong that there had been “another
potential pregnancy” involving a second couple.
A provincial government investigation has since confirmed the existence of
the second mother and that the woman was still pregnant, the official Xinhua
news agency reported.
The expectant mother and the twin girls from the first pregnancy will be
put under medical observation, an investigator told Xinhua.
The provincial government probe found He had “forged ethical review
papers” and “deliberately evaded supervision,” according to Xinhua.
He had “privately” organised a project team that included foreign staff
and used “technology of uncertain safety and effectiveness” for illegal human
embryo gene-editing, it said.
Investigators told Xinhua that the scientist was “pursuing personal fame”
and used “self-raised funds” for the controversial experiment.
Eight volunteer couples — HIV-positive fathers and HIV-negative mothers –
– signed up to He’s trial, investigators found, with one couple later
dropping out.
Details of the experiment — which has not been independently verified —
triggered an immediate backlash from the global scientific community and the
Chinese government ordered a halt to He’s research work days after it was
publicly announced.
Speaking at the genome summit in Hong Kong in November, He said he was
“proud” of altering the genes of the babies, given the stigma affecting AIDS
patients in the country.
But such gene-editing work is banned in most countries, including China.
He will be “dealt with seriously according to the law,” and his case will
be “handed over to public security organs for handling,” Xinhua said.
The scientist was educated at Stanford University in the US and recruited
back to China as part of Beijing’s “Thousand Talents Plan” to reverse brain
drain, according to a copy of He’s resume published on the website of the
Southern University of Science and Technology in Shenzhen.
He’s university has distanced itself from the researcher, saying he had
been on unpaid leave since February and had “seriously violated academic
ethics”.
He said the twins’ DNA was modified using CRISPR, a technique which allows
scientists to remove and replace a strand with pinpoint precision.
Experts worry meddling with the genome of an embryo could cause harm not
only to the individual but also future generations that inherit these same
changes.
BSS/AFP/ARS/1745 hrs